King Edward VII, then HRH The Prince of Wales, was Edward's godfather. It has been rumoured, his father, or even his grandfather.James believed his godfather was, in fact, his grandfather. The Prince was a frequent visitor to the shooting parties at West Dean Estate.

On 21 October 1909 West Dean House was chosen as the location in which HRH Edward VII opened, by remote control, the Royal Edward Institute for Tuberculosis in Montreal, Canada. As reported in the newspapers of the day, the King walked out of the Dining Room and pressed what looked like a bell-push. This sent an 'electric spark' transmitted from West Dean to Montreal where the opening ceremony was being held. When the current reached the Institute the doors of the building flew open. As the crowd entered the building all of the electric lights were switched on and the Union Jack was run up the flag pole. There is an alabaster plaque at the top of the marble stairs at West Dean House commemorating this event. The earliest reference to West Dean is in the Domesday Book (1086).

In 1964 Edward James conveyed his family mansion and 6,400 acre estate to the charitable trust The Edward James Foundation. The Grade II* Listed house is now home to the college internationally renowned for conservation and creative arts.